ID   H1G1.1c3
AC   CVCL_DC19
DR   Wikidata; Q54871984
RX   PubMed=11812924;
RX   PubMed=15096657;
RX   PubMed=21394221;
CC   Biotechnology: Cell line developed for CAFLUX (Chemically Activated FLUorescence eXpression) bioassay. CAFLUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
CC   Characteristics: Acts through the activation of a EGFP gene under the control of dioxin-response elements (DREs).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: C57L.
DI   NCIt; C38756; Hepatocellular carcinoma of the mouse
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0328 ! Hepa-1c1c7
SX   Female
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 29-06-23; Version: 9
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RX   PubMed=11812924; DOI=10.1093/toxsci/65.2.200;
RA   Nagy S.R., Sanborn J.R., Hammock B.D., Denison M.S.;
RT   "Development of a green fluorescent protein-based cell bioassay for
RT   the rapid and inexpensive detection and characterization of ah
RT   receptor agonists.";
RL   Toxicol. Sci. 65:200-210(2002).
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RX   PubMed=15096657; DOI=10.1002/biof.5520200102;
RA   Han D., Nagy S.R., Denison M.S.;
RT   "Comparison of recombinant cell bioassays for the detection of Ah
RT   receptor agonists.";
RL   BioFactors 20:11-22(2004).
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RX   PubMed=21394221; DOI=10.1007/s11426-010-0142-8;
RA   Zhao B., Baston D.S., Khan E., Sorrentino C., Denison M.S.;
RT   "Enhancing the response of CALUX and CAFLUX cell bioassays for
RT   quantitative detection of dioxin-like compounds.";
RL   Sci. China Chem. 53:1010-1016(2010).
//