ID   G16L7.5c1
AC   CVCL_DC18
DR   Wikidata; Q54835370
RX   PubMed=26366531;
CC   Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
CC   Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Transformant: ChEBI; CHEBI_50102; N-methyl-N-nitrosourea (NMU).
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
DI   NCIt; C134563; Guinea pig colon adenocarcinoma
OX   NCBI_TaxID=10141; ! Cavia porcellus (Guinea pig)
HI   CVCL_3463 ! GPC-16
SX   Female
AG   Adult
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 19-12-24; Version: 11
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RX   PubMed=26366531; DOI=10.1021/acs.est.5b02906; PMCID=PMC4772899;
RA   Brennan J.C., He G.-C., Tsutsumi T., Zhao J., Wirth E., Fulton M.H.,
RA   Denison M.S.;
RT   "Development of species-specific Ah receptor-responsive third
RT   generation CALUX cell lines with enhanced responsiveness and improved
RT   detection limits.";
RL   Environ. Sci. Technol. 49:11903-11912(2015).
//