ID   NEF
AC   CVCL_D900
DR   BTO; BTO_0005262
DR   Wikidata; Q54930387
RX   PubMed=1417788;
RX   PubMed=2246335;
RX   PubMed=2543678;
CC   Characteristics: Expresses ~300000 EGFR (PubMed=1417788).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3236; EGFR.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: NIH Swiss.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0594 ! NIH 3T3
SX   Male
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=1417788; DOI=10.1042/bj2870037; PMCID=PMC1133120;
RA   Spaargaren M., Wissink S., Defize L.H.K., de Laat S.W., Boonstra J.;
RT   "Characterization and identification of an
RT   epidermal-growth-factor-activated phospholipase A2.";
RL   Biochem. J. 287:37-43(1992).
//
RX   PubMed=2246335; DOI=10.1002/jcp.1041450223;
RA   van Belzen N., Spaargaren M., Verkleij A.J., Boonstra J.;
RT   "Interaction of epidermal growth factor receptors with the
RT   cytoskeleton is related to receptor clustering.";
RL   J. Cell. Physiol. 145:365-375(1990).
//
RX   PubMed=2543678; DOI=10.1016/S0021-9258(18)81674-X;
RA   Margolis B.L., Lax I., Kris R., Dombalagian M., Honegger A.,
RA   Howk R., Givol D., Ullrich A., Schlessinger J.;
RT   "All autophosphorylation sites of epidermal growth factor (EGF)
RT   receptor and HER2/neu are located in their carboxyl-terminal tails.
RT   Identification of a novel site in EGF receptor.";
RL   J. Biol. Chem. 264:10667-10671(1989).
//