ID   HPK-1A
AC   CVCL_D890
SY   HPK1A; HPK IA; HPKIA
DR   BTO; BTO_0005276
DR   Wikidata; Q54890290
RX   DOI=10.1007/978-1-4612-0411-4_3;
RX   PubMed=1618864;
RX   PubMed=1742725;
RX   PubMed=2556855;
RX   PubMed=2838778;
RX   PubMed=21439369;
CC   Virology: Contains 2 to 3 copies of the complete HPV16 genomes arranged in a head-to-tail fashion and integrated at a single chromosomal site.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Transformed cell line
DT   Created: 22-10-12; Last updated: 10-04-25; Version: 15
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RX   DOI=10.1007/978-1-4612-0411-4_3;
RA   Allen-Hoffmann, B. Lynn
RA   Sheibani, Nader
RA   Hatfield, Jill S.
RA   Rhim, Johng Sik
RT   "Use of immortalized human keratinocytes for the study of squamous
RT   differentiation and mutagenesis.";
RL   (In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim, Johng Sik & Dritschilo, Anatoly (eds.); pp.25-34; Humana Press; New York; USA (1990).
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RX   PubMed=1618864; DOI=10.1016/S0021-9258(18)42258-2;
RA   Kaiser, Stephanie M.
RA   Laneuville, Pierre
RA   Bernier, Suzanne Marie
RA   Rhim, Johng Sik
RA   Kremer, Richard
RA   Goltzman, David
RT   "Enhanced growth of a human keratinocyte cell line induced by
RT   antisense RNA for parathyroid hormone-related peptide.";
RL   J. Biol. Chem. 267:13623-13628(1992).
//
RX   PubMed=1742725;
RA   Henderson, Janet
RA   Sebag, Michael
RA   Rhim, Johng Sik
RA   Goltzman, David
RA   Kremer, Richard
RT   "Dysregulation of parathyroid hormone-like peptide expression and
RT   secretion in a keratinocyte model of tumor progression.";
RL   Cancer Res. 51:6521-6528(1991).
//
RX   PubMed=2556855; DOI=10.1016/0042-6822(89)90595-3;
RA   Durst, Matthias
RA   Gallahan, Dan
RA   Jay, Gilbert
RA   Rhim, Johng Sik
RT   "Glucocorticoid-enhanced neoplastic transformation of human
RT   keratinocytes by human papillomavirus type 16 and an activated ras
RT   oncogene.";
RL   Virology 173:767-771(1989).
//
RX   PubMed=2838778;
RA   Durst, Matthias
RA   Dzarlieva-Petrusevska, Rule T.
RA   Boukamp, Petra
RA   Fusenig, Norbert E.
RA   Gissmann, Lutz
RT   "Molecular and cytogenetic analysis of immortalized human primary
RT   keratinocytes obtained after transfection with human papillomavirus
RT   type 16 DNA.";
RL   Oncogene 1:251-256(1987).
//
RX   PubMed=21439369; DOI=10.1016/j.mcp.2011.03.003;
RA   Schmitt, Markus
RA   Pawlita, Michael
RT   "The HPV transcriptome in HPV16 positive cell lines.";
RL   Mol. Cell. Probes 25:108-113(2011).
//