ID   MM96
AC   CVCL_D848
SY   MM-96; MM 96
DR   cancercelllines; CVCL_D848
DR   Cosmic; 928749
DR   Wikidata; Q54906194
RX   PubMed=294576;
RX   PubMed=460945;
RX   PubMed=830403;
RX   PubMed=1697409;
RX   PubMed=2798328;
RX   PubMed=6187441;
RX   PubMed=6277475;
RX   PubMed=7217226;
RX   PubMed=7999427;
RX   PubMed=10070891;
RX   PubMed=17363583;
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17363583).
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   66Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 10-04-25; Version: 18
//
RX   PubMed=294576; DOI=10.3109/00313027909059039;
RA   Muir P.D., Gunz F.W.;
RT   "A cytogenetic study of eight human melanoma cell lines.";
RL   Pathology 11:597-606(1979).
//
RX   PubMed=460945; DOI=10.3109/00313027909061945;
RA   Pope J.H., Morrison L.E., Moss D.J., Parsons P.G., Dunne R.M.;
RT   "Human malignant melanoma cell lines.";
RL   Pathology 11:191-195(1979).
//
RX   PubMed=830403;
RA   Goss P.D., Parsons P.G.;
RT   "The effect of hyperthermia and melphalan on survival of human
RT   fibroblast strains and melanoma cell lines.";
RL   Cancer Res. 37:152-156(1977).
//
RX   PubMed=1697409;
RA   Chenevix-Trench G., Martin N.G., Ellem K.A.O.;
RT   "Gene expression in melanoma cell lines and cultured melanocytes:
RT   correlation between levels of c-src-1, c-myc and p53.";
RL   Oncogene 5:1187-1193(1990).
//
RX   PubMed=2798328; DOI=10.1111/j.1600-0749.1989.tb00217.x;
RA   Barkla D.H., Allen B.J., Brown J.K., Mountford M.H., Mishima Y.,
RA   Ichihashi M.;
RT   "Morphological changes in human melanoma cells following irradiation
RT   with thermal neutrons.";
RL   Pigment Cell Res. 2:345-348(1989).
//
RX   PubMed=6187441;
RA   Parsons P.G., Musk P., Goss P.D., Leah J.;
RT   "Effects of calcium depletion on human cells in vitro and the
RT   anomalous behavior of the human melanoma cell line MM170.";
RL   Cancer Res. 43:2081-2087(1983).
//
RX   PubMed=6277475;
RA   Frampton R.J., Suva L.J., Eisman J.A., Findlay D.M., Moore G.E.,
RA   Moseley J.M., Martin T.J.;
RT   "Presence of 1,25-dihydroxyvitamin D3 receptors in established human
RT   cancer cell lines in culture.";
RL   Cancer Res. 42:1116-1119(1982).
//
RX   PubMed=7217226; DOI=10.1002/jcp.1041070111;
RA   Sheridan J.W., Simmons R.J.;
RT   "Studies on a human melanoma cell line: effect of cell crowding and
RT   nutrient depletion on the biophysical and kinetic characteristics of
RT   the cells.";
RL   J. Cell. Physiol. 107:85-100(1981).
//
RX   PubMed=7999427; DOI=10.1016/0959-8049(94)90188-0;
RA   Marshall E.S., Matthews J.H.L., Shaw J.H.F., Nixon J., Tumewu P.,
RA   Finlay G.J., Holdaway K.M., Baguley B.C.;
RT   "Radiosensitivity of new and established human melanoma cell lines:
RT   comparison of [3H]thymidine incorporation and soft agar clonogenic
RT   assays.";
RL   Eur. J. Cancer 30A:1370-1376(1994).
//
RX   PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648;
RA   Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.;
RT   "p53 mutations in human cutaneous melanoma correlate with sun exposure
RT   but are not always involved in melanomagenesis.";
RL   Br. J. Cancer 79:921-926(1999).
//
RX   PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152;
RA   Stark M.S., Hayward N.K.;
RT   "Genome-wide loss of heterozygosity and copy number analysis in
RT   melanoma using high-density single-nucleotide polymorphism arrays.";
RL   Cancer Res. 67:2632-2642(2007).
//