ID   BT142
AC   CVCL_D718
DR   cancercelllines; CVCL_D718
DR   Cosmic; 1629581
DR   Cosmic; 2012330
DR   Wikidata; Q54798487
RX   PubMed=22166263;
RX   PubMed=33504762;
CC   Group: Cancer stem cell line.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132His (c.395G>A); ClinVar=VCV000156444; Zygosity=Heterozygous (PubMed=22166263).
CC   Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
DI   NCIt; C4050; Oligoastrocytoma
DI   ORDO; Orphanet_251656; Oligoastrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   38Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 18
CH   CVCL_X501 ! BT142 mut/-
//
RX   PubMed=33504762; DOI=10.1038/s41467-020-20752-6; PMCID=PMC7840755;
RA   Lita, Adrian
RA   Pliss, Artem
RA   Kuzmin, Andrey N.
RA   Yamasaki, Tomohiro
RA   Zhang, Lu-Min
RA   Dowdy, Tyrone
RA   Burks, Christina
RA   de Val, Natalia
RA   Celiku, Orieta
RA   Ruiz-Rodado, Victor
RA   Nicoli, Elena-Raluca
RA   Kruhlak, Michael J.
RA   Andresson, Thorkell
RA   Das, Sudipto
RA   Yang, Chun-Zhang
RA   Schmitt, Rebecca
RA   Herold-Mende, Christel
RA   Gilbert, Mark R.
RA   Prasad, Paras Nath
RA   Larion, Mioara
RT   "IDH1 mutations induce organelle defects via dysregulated
RT   phospholipids.";
RL   Nat. Commun. 12:614.1-614.16(2021).
//
RX   PubMed=22166263; DOI=10.1093/neuonc/nor207; PMCID=PMC3266388;
RA   Luchman, Hema Artee
RA   Stechishin, Owen D.M.
RA   Dang, N. Ha
RA   Blough, Michael D.
RA   Chesnelong, Charles
RA   Kelly, John J.P.
RA   Nguyen, Stephanie A.
RA   Chan, Jennifer Ai-Wen
RA   Weljie, Aalim M.
RA   Cairncross, J. Gregory
RA   Weiss, Samuel
RT   "An in vivo patient-derived model of endogenous IDH1-mutant glioma.";
RL   Neuro-oncol. 14:184-191(2012).
//