ID   HyCyte OCI-AML3 KO-hFGL2
AC   CVCL_D6C9
SY   hFGL2 knockout OCI-AML3
DR   Hysigen; CGKO-M2505
DR   Wikidata; Q127382046
CC   Population: Caucasian.
CC   Doubling time: 24-36 hours (Hysigen=CGKO-M2505).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 3696; FGL2.
CC   Sequence variation: Mutation; HGNC; 2978; DNMT3A; Simple; p.Arg882Cys (c.2644C>T); ClinVar=VCV000375882; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7910; NPM1; Simple; p.Trp288Cysfs*12 (c.860_863dupTCTG); ClinVar=VCV000013998; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1844 ! OCI-AML-3
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 10-09-24; Version: 2
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