ID   HyCyte HT-1080 KO-hSMARCA4
AC   CVCL_D6BS
SY   hSMARCA4 knockout HT-1080
DR   Hysigen; CGKO-M2389
DR   Wikidata; Q127382029
CC   Population: Caucasian.
CC   Doubling time: 24-48 hours (Hysigen=CGKO-M2389).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11100; SMARCA4.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
DI   NCIt; C3043; Fibrosarcoma
DI   ORDO; Orphanet_2030; Fibrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0317 ! HT-1080
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 19-12-24; Version: 3
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