ID   HTD114
AC   CVCL_D683
SY   HTD-114; HTD 114
DR   BTO; BTO:0004315
DR   cancercelllines; CVCL_D683
DR   Wikidata; Q54896609
RX   PubMed=6307822;
RX   PubMed=7510848;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
DI   NCIt; C3043; Fibrosarcoma
DI   ORDO; Orphanet_2030; Fibrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0317 ! HT-1080
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 05-10-23; Version: 20
//
RX   PubMed=6307822; DOI=10.1016/0378-1119(83)90106-3;
RA   Sikela J.M., Khan S.A., Feliciano E., Trill J.J., Tischfield J.A.,
RA   Stambrook P.J.;
RT   "Cloning and expression of a mouse adenine phosphoribosyltransferase
RT   gene.";
RL   Gene 22:219-228(1983).
//
RX   PubMed=7510848; DOI=10.1016/0165-1218(94)90122-8;
RA   Zhu Y., Bye S., Stambrook P.J., Tischfield J.A.;
RT   "Single-base deletion induced by benzo[a]pyrene diol epoxide at the
RT   adenine phosphoribosyltransferase locus in human fibrosarcoma cell
RT   lines.";
RL   Mutat. Res. 321:73-79(1994).
//