ID   A2780/CDDP
AC   CVCL_D619
DR   BTO; BTO:0005152
DR   cancercelllines; CVCL_D619
DR   Wikidata; Q54606602
RX   PubMed=15254775;
RX   PubMed=17269733;
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
DI   NCIt; C7979; Ovarian endometrioid adenocarcinoma
DI   ORDO; Orphanet_454723; Endometrioid carcinoma of ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0134 ! A2780
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 05-10-23; Version: 15
//
RX   PubMed=15254775; DOI=10.3892/ijmm.14.2.257;
RA   Li L., Luan Y.-Z., Wang G.-D., Tang B.-J., Li D.-R., Zhang W.,
RA   Li X.-P., Zhao J.-S., Ding H., Reed E., Li Q.-D.Q.;
RT   "Development and characterization of five cell models for
RT   chemoresistance studies of human ovarian carcinoma.";
RL   Int. J. Mol. Med. 14:257-264(2004).
//
RX   PubMed=17269733; DOI=10.1021/pr060402r;
RA   Yan X.-D., Pan L.-Y., Yuan Y., Lang J.-H., Mao N.;
RT   "Identification of platinum-resistance associated proteins through
RT   proteomic analysis of human ovarian cancer cells and their
RT   platinum-resistant sublines.";
RL   J. Proteome Res. 6:772-780(2007).
//