ID   CEC-32/chMx-Luc
AC   CVCL_D5YC
DR   Wikidata; Q127380429
RX   PubMed=7518167;
RX   PubMed=15035851;
CC   Group: Bird cell line.
CC   Problematic cell line: Misidentified. Parent cell line (CEC-32) was originally thought to be of chicken origin but found to be from quail.
CC   Characteristics: Used in a bioassay for the sensitive detection of chicken IFN (ChIFN) (PubMed=15035851).
CC   Characteristics: Expresses luciferase under the control of the IFN-inducible chicken gene Mx promoter (PubMed=7518167).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=93934; ! Coturnix japonica (Japanese quail)
HI   CVCL_D160 ! CEC-32
CA   Spontaneously immortalized cell line
DT   Created: 02-05-24; Last updated: 10-09-24; Version: 2
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RX   PubMed=7518167; DOI=10.1006/viro.1994.1464;
RA   Schumacher B., Bernasconi D., Schultz U., Staeheli P.;
RT   "The chicken Mx promoter contains an ISRE motif and confers interferon
RT   inducibility to a reporter gene in chick and monkey cells.";
RL   Virology 203:144-148(1994).
//
RX   PubMed=15035851; DOI=10.1089/107999004322917025;
RA   Schwarz H., Harlin O., Ohnemus A., Kaspers B., Staeheli P.;
RT   "Synthesis of IFN-beta by virus-infected chicken embryo cells
RT   demonstrated with specific antisera and a new bioassay.";
RL   J. Interferon Cytokine Res. 24:179-184(2004).
//