ID   MM2d
AC   CVCL_D5GY
DR   GEO; GSE5747
DR   GEO; GSE5750
DR   GEO; GSE108741
DR   RIKEN_BRC_EPD; rpc00103
DR   Wikidata; Q127382833
RX   PubMed=12000456;
RX   PubMed=12231968;
RX   PubMed=14756764;
RX   PubMed=16408177;
RX   PubMed=16739567;
RX   PubMed=19368694;
RX   PubMed=20130883;
RX   PubMed=21613568;
RX   PubMed=24134884;
CC   Group: Plant cell line.
CC   Characteristics: Rapid cell proliferation (PubMed=12000456).
CC   Characteristics: Grows in darkness (PubMed=12000456).
CC   Characteristics: The cell cycle can be synchronized by removing and re-supplying sucrose or with aphidicolin (PubMed=12000456; PubMed=16739567).
CC   Characteristics: Can be genetically transformed with Agrobacterium (PubMed=14756764).
CC   Characteristics: Can be used to prepare protoplasts (PubMed=24134884).
CC   Omics: Genomics; ChIP-seq; A.thaliana RBR1.
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Stem; PO=PO_0009047.
CC   Breed/subspecies: Cultivar Landsberg erecta.
OX   NCBI_TaxID=3702; ! Arabidopsis thaliana (Mouse-ear cress)
HI   CVCL_D5GX ! MM1
CA   Spontaneously immortalized cell line
DT   Created: 02-05-24; Last updated: 10-04-25; Version: 3
CH   CVCL_D5GZ ! MM2d-LS
CH   CVCL_D5H0 ! PSB-D
//
RX   PubMed=12231968; DOI=10.1104/pp.103.2.621; PMCID=PMC159023;
RA   May, Mike J.
RA   Leaver, Christopher John
RT   "Oxidative stimulation of glutathione synthesis in Arabidopsis
RT   thaliana suspension cultures.";
RL   Plant Physiol. 103:621-627(1993).
//
RX   PubMed=16739567; DOI=10.1385/1-59745-003-0:45;
RA   Menges, Margit
RA   Murray, James A.H.
RT   "Synchronization, transformation, and cryopreservation of
RT   suspension-cultured cells.";
RL   Methods Mol. Biol. 323:45-61(2006).
//
RX   PubMed=21613568; DOI=10.1073/pnas.1103584108; PMCID=PMC3116379;
RA   Adachi, Sumiko
RA   Minamisawa, Kazunori
RA   Okushima, Yoko
RA   Inagaki, Soichi
RA   Yoshiyama, Kaoru
RA   Kondou, Youichi
RA   Kaminuma, Eli
RA   Kawashima, Mika
RA   Toyoda, Tetsuro
RA   Matsui, Minami
RA   Kurihara, Daisuke
RA   Matsunaga, Sachihiro
RA   Umeda, Masaaki
RT   "Programmed induction of endoreduplication by DNA double-strand breaks
RT   in Arabidopsis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:10004-10009(2011).
//
RX   PubMed=19368694; DOI=10.1111/j.1365-313x.2009.03884.x;
RA   Takatsuka, Hirotomo
RA   Ohno, Ryoko
RA   Umeda, Masaaki
RT   "The Arabidopsis cyclin-dependent kinase-activating kinase CDKF;1 is a
RT   major regulator of cell proliferation and cell expansion but is
RT   dispensable for CDKA activation.";
RL   Plant J. 59:475-487(2009).
//
RX   PubMed=24134884; DOI=10.1104/pp.113.225607; PMCID=PMC3850192;
RA   Hamada, Takahiro
RA   Nagasaki-Takeuchi, Nahoko
RA   Kato, Takehide
RA   Fujiwara, Masayuki
RA   Sonobe, Seiji
RA   Fukao, Yoichiro
RA   Hashimoto, Takashi
RT   "Purification and characterization of novel microtubule-associated
RT   proteins from Arabidopsis cell suspension cultures.";
RL   Plant Physiol. 163:1804-1816(2013).
//
RX   PubMed=12000456; DOI=10.1046/j.1365-313x.2002.01274.x;
RA   Menges, Margit
RA   Murray, James A.H.
RT   "Synchronous Arabidopsis suspension cultures for analysis of cell-cycle
RT   gene activity.";
RL   Plant J. 30:203-212(2002).
//
RX   PubMed=16408177; DOI=10.1007/s00299-005-0075-4;
RA   Kono, Atsushi
RA   Ohno, Ryoko
RA   Umeda-Hara, Chikage
RA   Uchimiya, Hirofumi
RA   Umeda, Masaaki
RT   "A distinct type of cyclin D, CYCD4;2, involved in the activation of
RT   cell division in Arabidopsis.";
RL   Plant Cell Rep. 25:540-545(2006).
//
RX   PubMed=20130883; DOI=10.1007/s00299-010-0817-9;
RA   Takahashi, Ikuo
RA   Kojima, Shoko
RA   Sakaguchi, Norihiro
RA   Umeda-Hara, Chikage
RA   Umeda, Masaaki
RT   "Two Arabidopsis cyclin A3s possess G1 cyclin-like features.";
RL   Plant Cell Rep. 29:307-315(2010).
//
RX   PubMed=14756764; DOI=10.1046/j.1365-313x.2003.01980.x;
RA   Menges, Margit
RA   Murray, James A.H.
RT   "Cryopreservation of transformed and wild-type Arabidopsis and tobacco
RT   cell suspension cultures.";
RL   Plant J. 37:635-644(2004).
//