ID   HeLa S3 RUBCNL KO/HaloTag7-LC3
AC   CVCL_D5AM
SY   Pacer KO S3 HeLa + HaloTag7-LC3
DR   Wikidata; Q127381699
RX   PubMed=38728007;
CC   Population: African American.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:20420; RUBCNL.
CC   Genetic integration: Method=Transduction; Gene=RGD; 621315; Map1lc3b.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P0A3G2; Rhodococcus rhodochrous dhaA (Note=Mutated = HaloTag).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D5AH ! HeLa S3 RUBCNL KO clone 17
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 10-04-25; Version: 4
//
RX   PubMed=38728007; DOI=10.1083/jcb.202309015; PMCID=PMC11090050;
RA   Tudorica D.A., Basak B., Puerta Cordova A.S., Khuu G., Rose K.M.,
RA   Lazarou M., Holzbaur E.L.F., Hurley J.H.;
RT   "A RAB7A phosphoswitch coordinates Rubicon homology protein regulation
RT   of parkin-dependent mitophagy.";
RL   J. Cell Biol. 223:e202309015.1-e202309015.18(2024).
//