ID   HeLa S3 RUBCN KO/HA-Parkin/HaloTag7-mGFP
AC   CVCL_D5AJ
SY   Rubicon KO S3 HeLa + HA-Parkin/pSu9 + HaloTag7-mGFP
DR   Wikidata; Q127381694
RX   PubMed=38728007;
CC   Population: African American.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:28991; RUBCN.
CC   Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:8607; PRKN (Note=With a N-terminal HA tag).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P0A3G2; Rhodococcus rhodochrous dhaA (Note=Mutated = HaloTag).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D5AG ! HeLa S3 RUBCN KO clone 15
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 14-08-25; Version: 5
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RX   PubMed=38728007; DOI=10.1083/jcb.202309015; PMCID=PMC11090050;
RA   Tudorica, Dan Alexandru
RA   Basak, Bishal
RA   Puerta Cordova, Alexia S.
RA   Khuu, Grace
RA   Rose, Kevin M.
RA   Lazarou, Michael
RA   Holzbaur, Erika L.F.
RA   Hurley, James Herschel
RT   "A RAB7A phosphoswitch coordinates Rubicon homology protein regulation
RT   of parkin-dependent mitophagy.";
RL   J. Cell Biol. 223:e202309015.1-e202309015.18(2024).
//