ID   CW1474
AC   CVCL_D4Z7
DR   ATCC; CRL-3529
DR   Wikidata; Q127380727
RX   PubMed=35934060;
RX   PubMed=37182784;
CC   Population: Caucasian.
CC   Characteristics: Established from a patient-derived xenograft (PubMed=35934060).
CC   Doubling time: 41 hours (Direct_author_submission).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly279_Thr284del; Zygosity=Homozygous (Direct_author_submission).
CC   Omics: Genomics; Whole exome sequencing.
CC   Miscellaneous: Doubling time, TP53 mutation, age at sampling and ethnic origin of patient from personal communication of Blum, Andrew E.
CC   Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
DI   NCIt; C4025; Esophageal adenocarcinoma
DI   ORDO; Orphanet_99976; Adenocarcinoma of the esophagus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   86Y
CA   Cancer cell line
DT   Created: 02-05-24; Last updated: 10-04-25; Version: 4
//
RX   PubMed=35934060; DOI=10.1053/j.gastro.2022.07.073; PMCID=PMC9613531;
RA   Blum A.E., Ravillah D., Katabathula R.M., Khalighi S., Varadan V.,
RA   Guda K.;
RG   Betrnet Consortium;
RT   "HNF4A defines molecular subtypes and vulnerability to transforming
RT   growth factor beta-pathway targeted therapies in cancers of the
RT   distal esophagus.";
RL   Gastroenterology 163:1457-1460(2022).
//
RX   PubMed=37182784; DOI=10.1053/j.gastro.2023.04.037; PMCID=PMC10524377;
RA   Ravillah D., Kieber-Emmons A.L., Singh S., Keerthy K.S., Blum A.E.,
RA   Guda K.;
RG   Betrnet Consortium;
RT   "Discovery and initial characterization of long intergenic noncoding
RT   RNAs associated with esophageal adenocarcinoma.";
RL   Gastroenterology 165:505-508.e7(2023).
//