ID   1321N1-SLC4A8-KO-c6
AC   CVCL_D4FD
SY   CE0574-W
DR   Wikidata; Q127378612
WW   Info; RESOLUTE; CE0574-W; https://re-solute.eu/resources/reagents
CC   Problematic cell line: Contaminated. Ancestral cell line (U-118MG) has been shown to be a U-138MG derivative.
CC   Part of: Research Empowerment on Solute Carriers (RESOLUTE) KO cell line panel.
CC   Population: Caucasian.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11034; SLC4A8.
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; c.1026+1G>T (IVS8+1G>T); ClinVar=VCV000635377; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0110 ! 1321N1
SX   Male
AG   47Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 10-04-25; Version: 4
//