ID   HEK293 FRT FURIN KO
AC   CVCL_D4C5
SY   DeltaFur293; HEK293 DeltaFUR
DR   Wikidata; Q127381644
RX   DOI=10.1101/2023.05.31.542721;
CC   Characteristics: Contain a single stably integrated Flp recombinase recognition target (FRT) site at a transcriptionally active genomic locus (from parent cell line).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8568; FURIN (Note=Exon 2 105 bp deletion).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
ST   Source(s): DOI=10.1101/2023.05.31.542721
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D10S1248: 14
ST   D12S391: 19,21
ST   D13S317: 12,14
ST   D16S539: 9,13
ST   D18S51: 17,18
ST   D19S433: 18
ST   D1S1656: 15,17.3
ST   D21S11: 28,30.2
ST   D22S1045: 16
ST   D2S1338: 19
ST   D2S441: 11,15
ST   D3S1358: 15,17
ST   D5S818: 8
ST   D7S820: 11,12
ST   D8S1179: 12
ST   FGA: 23
ST   SE33: 17
ST   TH01: 7,9.3
ST   TPOX: 11
ST   vWA: 16,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D4C4 ! HEK293 FRT
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 30-01-24; Last updated: 10-04-25; Version: 5
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RX   DOI=10.1101/2023.05.31.542721;
RA   Grossman B.D., Sanford J.D., Zhu Y.-Y., Zeller C.B., Weldon J.E.;
RT   "Intracellular trafficking of furin enhances cellular intoxication by
RT   recombinant immunotoxins based on Pseudomonas exotoxin A.";
RL   bioRxiv 2023:05.31.542721-05.31.542721(2023).
//