ID   LNCaP-r
AC   CVCL_D3W5
RX   PubMed=2734981;
RX   PubMed=4048015;
RX   PubMed=10092147;
CC   Population: Caucasian.
CC   Characteristics: Resistant to androgen (PubMed=4048015).
CC   Sequence variation: Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1379 ! LNCaP clone FGC
SX   Male
AG   50Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 30-01-24; Version: 1
//
RX   PubMed=2734981; DOI=10.1007/BF00262025;
RA   Konig J.J., Kamst E., Hagemeijer A., Romijn J.C., Horoszewicz J.S.,
RA   Schroder F.H.;
RT   "Cytogenetic characterization of several androgen responsive and
RT   unresponsive sublines of the human prostatic carcinoma cell line
RT   LNCaP.";
RL   Urol. Res. 17:79-86(1989).
//
RX   PubMed=4048015; DOI=10.1002/pros.2990070208;
RA   Hasenson M., Hartley-Asp B., Kihlfors C., Lundin A., Gustafsson J.-A.,
RA   Pousette A.;
RT   "Effect of hormones on growth and ATP content of a human prostatic
RT   carcinoma cell line, LNCaP-r.";
RL   Prostate 7:183-194(1985).
//
RX   PubMed=10092147; DOI=10.1007/s002400050082;
RA   Konig J.J., Teubel W.J., van Steenbrugge G.J., Romijn J.C.,
RA   Hagemeijer A.;
RT   "Characterization of chromosome 8 aberrations in the prostate cancer
RT   cell line LNCaP-FGC and sublines.";
RL   Urol. Res. 27:3-8(1999).
//