ID   CHO/ASCT2
AC   CVCL_D3PI
SY   ASCT2/CHO
DR   Wikidata; Q127380485
RX   PubMed=27865832;
CC   Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10943; SLC1A5 (Note=With a C-terminal mycHis6 tag).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_7180 ! CHO-DG44
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 30-01-24; Last updated: 19-12-24; Version: 3
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RX   PubMed=27865832; DOI=10.1016/j.bbrc.2016.11.089;
RA   Suzuki M., Toki H., Furuya A., Ando H.;
RT   "Establishment of monoclonal antibodies against cell surface domains
RT   of ASCT2/SLC1A5 and their inhibition of glutamine-dependent tumor
RT   cell growth.";
RL   Biochem. Biophys. Res. Commun. 482:651-657(2017).
//