ID   iBMK D3.zeo-2RED 2
AC   CVCL_D3J4
SY   D3.zeo-2RED 2
DR   Wikidata; Q127382216
RX   PubMed=15314031;
RX   PubMed=18603117;
CC   Knockout cell: Method=KO mouse; MGI; MGI:1097161; Bak1.
CC   Knockout cell: Method=KO mouse; MGI; MGI:99702; Bax.
CC   Genetic integration: Method=Transfection; Gene=FPbase; TXLFX; DsRed2 (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_D3GQ ! iBMK D3.zeo-2
SX   Sex unspecified
AG   5D
CA   Transformed cell line
DT   Created: 30-01-24; Last updated: 10-04-25; Version: 3
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RX   PubMed=15314031; DOI=10.1101/gad.1204904; PMCID=PMC515288;
RA   Nelson D.A., Tan T.-T., Rabson A.B., Anderson D., Degenhardt K.,
RA   White E.;
RT   "Hypoxia and defective apoptosis drive genomic instability and
RT   tumorigenesis.";
RL   Genes Dev. 18:2095-2107(2004).
//
RX   PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4;
RA   Mathew R., Degenhardt K., Haramaty L., Karp C.M., White E.;
RT   "Immortalized mouse epithelial cell models to study the role of
RT   apoptosis in cancer.";
RL   Methods Enzymol. 446:77-106(2008).
//