ID   iBMK WB-13
AC   CVCL_D3HJ
SY   WB-13
DR   Wikidata; Q127382290
RX   PubMed=16843265;
RX   PubMed=17510285;
RX   PubMed=18603117;
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:990; BCL2.
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_D3G4 ! iBMK W4
SX   Sex unspecified
AG   5D
CA   Transformed cell line
DT   Created: 30-01-24; Last updated: 10-04-25; Version: 4
//
RX   PubMed=16843265; DOI=10.1016/j.ccr.2006.06.001; PMCID=PMC2857533;
RA   Degenhardt K., Mathew R., Beaudoin B., Bray K., Anderson D., Chen G.-H.,
RA   Mukherjee C., Shi Y.-F., Gelinas C., Fan Y.-J., Nelson D.A., Jin S.-K.,
RA   White E.;
RT   "Autophagy promotes tumor cell survival and restricts necrosis,
RT   inflammation, and tumorigenesis.";
RL   Cancer Cell 10:51-64(2006).
//
RX   PubMed=17510285; DOI=10.1101/gad.1545107; PMCID=PMC1877749;
RA   Mathew R., Kongara S., Beaudoin B., Karp C.M., Bray K., Degenhardt K.,
RA   Chen G.-H., Jin S.-K., White E.;
RT   "Autophagy suppresses tumor progression by limiting chromosomal
RT   instability.";
RL   Genes Dev. 21:1367-1381(2007).
//
RX   PubMed=18603117; DOI=10.1016/S0076-6879(08)01605-4;
RA   Mathew R., Degenhardt K., Haramaty L., Karp C.M., White E.;
RT   "Immortalized mouse epithelial cell models to study the role of
RT   apoptosis in cancer.";
RL   Methods Enzymol. 446:77-106(2008).
//