ID   U-2 OS/IDH2-WT
AC   CVCL_D3DN
DR   Wikidata; Q127384430
RX   PubMed=25753205;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5383; IDH2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 19-12-24; Version: 3
//
RX   PubMed=25753205; DOI=10.1016/j.bbrc.2015.02.162;
RA   Liu X., Ogasawara S., Kaneko M.K., Oki H., Hozumi Y., Goto K.,
RA   Takagi M., Kato Y.;
RT   "A novel monoclonal antibody SMab-2 recognizes endogenous IDH2-R172S
RT   of chondrosarcoma.";
RL   Biochem. Biophys. Res. Commun. 459:636-642(2015).
//