ID   LN229/mEGFR
AC   CVCL_D2SJ
DR   Wikidata; Q127382610
RX   PubMed=37489364;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:6597; LIFR; Simple; p.Pro1060Ala (c.3178C>G); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9811; RAD21; Simple; p.Gln132Ter (c.394C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro98Leu (c.293C>T); ClinVar=VCV000528236; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:95294; Egfr (Note=With a N-terminal GVAMPGAEDDVV = PA-tag).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Derived from site: In situ; Brain, right frontal parieto-occipital cortex.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0393 ! LN-229
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 19-12-24; Version: 3
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RX   PubMed=37489364; DOI=10.3390/antib12030042; PMCID=PMC10366908;
RA   Goto N., Suzuki H., Tanaka T., Ishikawa K., Ouchida T., Kaneko M.K.,
RA   Kato Y.;
RT   "EMab-300 detects mouse epidermal growth factor receptor-expressing
RT   cancer cell lines in flow cytometry.";
RL   Antibodies (Basel) 12:42.1-42.11(2023).
//