ID   HBT-3
AC   CVCL_D281
SY   HBT3
DR   BioSample; SAMN03151699
DR   Wikidata; Q54881458
RX   CelloPub=CLPUB00262;
RX   DOI=10.1007/978-1-4757-1647-4_13;
RX   PubMed=1246601;
RX   PubMed=4344270;
RX   PubMed=4469665;
RX   PubMed=20143388;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=4469665; PubMed=20143388). Originally thought to originate from a breast carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00052.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 02-05-24; Version: 21
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RX   CelloPub=CLPUB00262;
RA   Gold M.;
RT   "A conspiracy of cells. One woman's immortal legacy and the medical
RT   scandal it caused.";
RL   (In book) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany; USA (1986).
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RX   DOI=10.1007/978-1-4757-1647-4_13;
RA   Biedler J.L.;
RT   "Chromosome abnormalities in human tumor cells in culture.";
RL   (In book chapter) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York; USA (1975).
//
RX   PubMed=1246601; DOI=10.1126/science.1246601;
RA   Nelson-Rees W.A., Flandermeyer R.R.;
RT   "HeLa cultures defined.";
RL   Science 191:96-98(1976).
//
RX   PubMed=4344270; DOI=10.3181/00379727-141-36850;
RA   Bassin R.H., Plata E.J., Gerwin B.I., Mattern C.F.T., Haapala D.K.,
RA   Chu E.W.;
RT   "Isolation of a continuous epithelioid cell line, HBT-3, from a human
RT   breast carcinoma.";
RL   Proc. Soc. Exp. Biol. Med. 141:673-680(1972).
//
RX   PubMed=4469665; DOI=10.1126/science.184.4141.1093;
RA   Nelson-Rees W.A., Flandermeyer R.R., Hawthorne P.K.;
RT   "Banded marker chromosomes as indicators of intraspecies cellular
RT   contamination.";
RL   Science 184:1093-1096(1974).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//