AC   CVCL_D279
DR   BioSample; SAMN03151679
DR   Wikidata; Q54828575
RX   PubMed=1198998;
RX   PubMed=1246601;
RX   PubMed=4472134;
RX   PubMed=20143388;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=4472134; PubMed=20143388). Originally thought to originate from a 41 year old patient with an astrocytoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00040.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 02-05-24; Version: 22
RX   PubMed=1198998;
RA   Beniumovich M.S.;
RT   "Characteristics of a stable long-term cell line obtained from a
RT   dedifferentiated human astrocytoma.";
RL   Vopr. Neirokhir. 39:20-26(1975).
RX   PubMed=1246601; DOI=10.1126/science.1246601;
RA   Nelson-Rees W.A., Flandermeyer R.R.;
RT   "HeLa cultures defined.";
RL   Science 191:96-98(1976).
RX   PubMed=4472134; DOI=10.1093/jnci/53.3.751;
RA   Nelson-Rees W.A., Zhdanov V.M., Hawthorne P.K., Flandermeyer R.R.;
RT   "HeLa-like marker chromosomes and type-A variant glucose-6-phosphate
RT   dehydrogenase isoenzyme in human cell cultures producing Mason-Pfizer
RT   monkey virus-like particles.";
RL   J. Natl. Cancer Inst. 53:751-757(1974).
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).