ID   MGG8
AC   CVCL_D1H4
SY   MGG-8
DR   BTO; BTO_0006545
DR   GEO; GSM1306341
DR   GEO; GSM1306344
DR   GEO; GSM1324081
DR   GEO; GSM1324082
DR   GEO; GSM1324083
DR   GEO; GSM1324090
DR   GEO; GSM1324091
DR   GEO; GSM1324092
DR   GEO; GSM1324093
DR   GEO; GSM1324094
DR   GEO; GSM1324095
DR   GEO; GSM1324096
DR   GEO; GSM1324097
DR   Wikidata; Q127382825
RX   PubMed=22067563;
RX   PubMed=24726434;
RX   PubMed=27564115;
CC   Group: Cancer stem cell line.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=22067563).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (PubMed=22067563).
CC   Omics: Genomics; ChIP-seq; H3K27ac.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 10-04-25; Version: 4
//
RX   PubMed=22067563; DOI=10.1093/neuonc/nor195; PMCID=PMC3266381;
RA   Wakimoto H., Mohapatra G., Kanai R., Curry W.T. Jr., Yip S., Nitta M.,
RA   Patel A.P., Barnard Z.R., Stemmer-Rachamimov A.O., Louis D.N.,
RA   Martuza R.L., Rabkin S.D.;
RT   "Maintenance of primary tumor phenotype and genotype in glioblastoma
RT   stem cells.";
RL   Neuro-oncol. 14:132-144(2012).
//
RX   PubMed=24726434; DOI=10.1016/j.cell.2014.02.030; PMCID=PMC4004670;
RA   Suva M.L., Rheinbay E., Gillespie S.M., Patel A.P., Wakimoto H.,
RA   Rabkin S.D., Riggi N., Chi A.S., Cahill D.P., Nahed B.V., Curry W.T. Jr.,
RA   Martuza R.L., Rivera M.N., Rossetti N., Kasif S., Beik S., Kadri S.,
RA   Tirosh I., Wortman I., Shalek A.K., Rozenblatt-Rosen O., Regev A.,
RA   Louis D.N., Bernstein B.E.;
RT   "Reconstructing and reprogramming the tumor-propagating potential of
RT   glioblastoma stem-like cells.";
RL   Cell 157:580-594(2014).
//
RX   PubMed=27564115; DOI=10.18632/oncotarget.11589; PMCID=PMC5325344;
RA   Wilson T.J., Zamler D.B., Doherty R., Castro M.G., Lowenstein P.R.;
RT   "Reversibility of glioma stem cells' phenotypes explains their complex
RT   in vitro and in vivo behavior: Discovery of a novel
RT   neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using
RT   the genomic landscape of human glioma stem cells as a discovery
RT   tool.";
RL   Oncotarget 7:63020-63041(2016).
//