ID   A2780/ACRP
AC   CVCL_D157
SY   ACRP
DR   BCRJ; 0036
DR   cancercelllines; CVCL_D157
DR   Wikidata; Q54606587
RX   PubMed=12726863;
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
ST   Source(s): BCRJ=0036
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 12,13
ST   D16S539: 11,13
ST   D18S51: 16,18
ST   D19S433: 12
ST   D21S11: 28
ST   D2S1338: 21,22
ST   D3S1358: 14,16
ST   D5S818: 11,12
ST   D7S820: 10
ST   D8S1179: 15,17
ST   FGA: 19,23
ST   TH01: 6
ST   TPOX: 8,10
ST   vWA: 15,16
DI   NCIt; C7979; Ovarian endometrioid adenocarcinoma
DI   ORDO; Orphanet_454723; Endometrioid carcinoma of ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0134 ! A2780
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 02-05-24; Version: 17
//
RX   PubMed=12726863; DOI=10.1016/S1535-6108(03)00058-8;
RA   Sherman-Baust C.A., Weeraratna A.T., Rangel L.B.A., Pizer E.S.,
RA   Cho K.R., Schwartz D.R., Shock T., Morin P.J.;
RT   "Remodeling of the extracellular matrix through overexpression of
RT   collagen VI contributes to cisplatin resistance in ovarian cancer
RT   cells.";
RL   Cancer Cell 3:377-386(2003).
//