ID   MRIi016-A-2
AC   CVCL_D0EB
SY   B7 ctrl SHOX2 KO; UKHGi017-A-2
DR   BioSamples; SAMEA112465910
DR   hPSCreg; MRIi016-A-2
DR   Wikidata; Q123033124
RX   PubMed=37028180;
CC   From: Institute of Human Genetics, University Hospital Heidelberg; Heidelberg; Germany.
CC   Population: Caucasian.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10854; SHOX2.
CC   Sequence variation: Mutation; HGNC; HGNC:10854; SHOX2; Simple_corrected; c.*28T>C; dbSNP=rs138912749; Zygosity=Heterozygous; Note=By CRISPR/Cas9 (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C50466; Atrial fibrillation
DI   ORDO; Orphanet_334; Familial atrial fibrillation
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D0EA ! MRIi016-A-1
SX   Male
AG   45Y
CA   Induced pluripotent stem cell
DT   Created: 05-10-23; Last updated: 19-12-24; Version: 3
//
RX   PubMed=37028180; DOI=10.1016/j.scr.2023.103089;
RA   Radecke K., Gore A., Burau K., Laugsch M., Kohler K., Rappold G.A.,
RA   Hoffmann S.;
RT   "Generation of two homozygous SHOX2 knock-out human induced
RT   pluripotent stem cell lines using CRISPR/Cas9.";
RL   Stem Cell Res. 69:103089-103089(2023).
//