ID   HES-4
AC   CVCL_D094
SY   HES 4; HES4; ES04; ESIBIOe004-A; ESIBIe004-A
DR   BioSample; SAMN03471891
DR   GEO; GSM288338
DR   GEO; GSM1040245
DR   GEO; GSM1040315
DR   hPSCreg; ESIBIe004-A
DR   ISCR; 97
DR   SKIP; SKIP001477
DR   SKIP; SKIP001944
DR   WiCell; es04
DR   Wikidata; Q54882908
RX   PubMed=17570852;
RX   PubMed=17572666;
RX   PubMed=22802639;
RX   PubMed=23117585;
RX   PubMed=24259714;
WW   https://stemcelldb.nih.gov/cellLineDetails.do?id=10
CC   From: ESI BIO - BioTime, Inc. (ES Cell International).
CC   Registration: Swiss research registry; BAG-hES-IMP-0006.
CC   Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC03-02.
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis.
ST   Source(s): WiCell
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 10,11
ST   D16S539: 9,11
ST   D5S818: 10,12
ST   D7S820: 9,13
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 17,19
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 22-10-12; Last updated: 19-12-19; Version: 16
//
RX   PubMed=17570852; DOI=10.1186/gb-2007-8-6-r113;
RA   Hirst M., Delaney A., Rogers S.A., Schnerch A., Persaud D.R.,
RA   O'Connor M.D., Zeng T., Moksa M., Fichter K., Mah D., Go A.,
RA   Morin R.D., Baross A., Zhao Y.-J., Khattra J., Prabhu A.-L., Pandoh P.,
RA   McDonald H., Asano J., Dhalla N., Ma K., Lee S., Ally A., Chahal N.,
RA   Menzies S., Siddiqui A., Holt R., Jones S., Gerhard D.S.,
RA   Thomson J.A., Eaves C.J., Marra M.A.;
RT   "LongSAGE profiling of nine human embryonic stem cell lines.";
RL   Genome Biol. 8:R113.1-R113.12(2007).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Pera R.A.R., Reubinoff B.E., Robins A.J., Rossant J.,
RA   Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward D.,
RA   Weaver T.A., Young L.A., Zhang W.-D.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=22802639; DOI=10.1073/pnas.1209979109;
RA   Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N.,
RA   Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S.;
RT   "Donor-dependent variations in hepatic differentiation from
RT   human-induced pluripotent stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012).
//
RX   PubMed=23117585; DOI=10.1016/j.scr.2012.09.002;
RA   Mallon B.S., Chenoweth J.G., Johnson K.R., Hamilton R.S., Tesar P.J.,
RA   Yavatkar A.S., Tyson L.J., Park K., Chen K.G., Fann Y.C., McKay R.D.G.;
RT   "StemCellDB: the human pluripotent stem cell database at the National
RT   Institutes of Health.";
RL   Stem Cell Res. 10:57-66(2013).
//
RX   PubMed=24259714; DOI=10.1073/pnas.1319061110;
RA   Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H.,
RA   Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N.,
RA   Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J.,
RA   Yamanaka S.;
RT   "Differentiation-defective phenotypes revealed by large-scale analyses
RT   of human pluripotent stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013).
//