ID   M18/B7
AC   CVCL_D030
DR   cancercelllines; CVCL_D030
DR   ESTDAB; ESTDAB-041
DR   Wikidata; Q54903494
RX   PubMed=15592718;
RX   PubMed=19340423;
CC   HLA typing: A*29:02:01,29:02:01; B*49:01,49:01; C*07:01:01,07:01:01; DPB1*02:01:02,03:01:01; DQB1*03:02,03:01:01; DRB1*04:05:01,04:07:01 (PubMed=15592718).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1700; CD80.
ST   Source(s): ESTDAB=ESTDAB-041
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11
ST   D3S1358: 14,16
ST   D5S818: 11
ST   D7S820: 8
ST   FGA: 21,23
ST   TH01: 8
ST   TPOX: 11
ST   vWA: 17
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D029 ! M18
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966;
RA   Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A.,
RA   Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G.,
RA   Garrido F.;
RT   "High frequency of homozygosity of the HLA region in melanoma cell
RT   lines reveals a pattern compatible with extensive loss of
RT   heterozygosity.";
RL   Cancer Immunol. Immunother. 54:141-148(2005).
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RX   PubMed=19340423; DOI=10.1007/s00262-009-0701-z; PMCID=PMC11030131;
RA   Mendez R., Aptsiauri N., Del Campo A., Maleno I., Cabrera T.,
RA   Ruiz-Cabello Osuna F., Garrido F., Garcia-Lora A.;
RT   "HLA and melanoma: multiple alterations in HLA class I and II
RT   expression in human melanoma cell lines from ESTDAB cell bank.";
RL   Cancer Immunol. Immunother. 58:1507-1515(2009).
//