ID   DS2-iPS1
AC   CVCL_D013
SY   DS2-IPS1
DR   Wikidata; Q54831441
RX   Patent=US20110151447;
RX   PubMed=18691744;
RX   PubMed=23045682;
CC   From: Children's Hospital Boston; Boston; USA.
CC   Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C2993; Down syndrome
DI   ORDO; Orphanet_870; Down syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_D014 ! DS2-iPS10
SX   Male
AG   1M
CA   Induced pluripotent stem cell
DT   Created: 22-10-12; Last updated: 10-09-24; Version: 15
//
RX   Patent=US20110151447;
RA   Park, In-Hyun
RA   Daley, George Quentin
RA   Agarwal, Suneet
RA   Lerou, Paul Hubert
RT   "Method to produce induced pluripotent stem (iPS) cells from
RT   non-embryonic human cells.";
RL   Patent number US20110151447, 23-Jun-2011.
//
RX   PubMed=18691744; DOI=10.1016/j.cell.2008.07.041; PMCID=PMC2633781;
RA   Park, In-Hyun
RA   Arora, Natasha
RA   Huo, Hong-Guang
RA   Maherali, Nimet
RA   Ahfeldt, Tim
RA   Shimamura, Akiko
RA   Lensch, M. William
RA   Cowan, Chad A.
RA   Hochedlinger, Konrad
RA   Daley, George Quentin
RT   "Disease-specific induced pluripotent stem cells.";
RL   Cell 134:877-886(2008).
//
RX   PubMed=23045682; DOI=10.1073/pnas.1215468109; PMCID=PMC3491455;
RA   MacLean, Glenn A.
RA   Menne, Tobias F.
RA   Guo, Guo-Ji
RA   Sanchez, Danielle J.
RA   Park, In-Hyun
RA   Daley, George Quentin
RA   Orkin, Stuart Holland
RT   "Altered hematopoiesis in trisomy 21 as revealed through in vitro
RT   differentiation of isogenic human pluripotent cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:17567-17572(2012).
//