ID   FS 6
AC   CVCL_CW15
SY   FS6
DR   ATCC; CRL-3099
DR   Wikidata; Q54835183
RX   PubMed=17952114;
CC   Characteristics: Provides a powerful and convenient model for assaying potential tumor promoters and for testing potential antitumor and antiproliferative agents that might act on the v-Ha-ras pathways (ATCC=CRL-3099).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P01115; Harvey murine sarcoma virus H-Ras (V-Ha-ras).
CC   Transformant: Activated HRAS.
CC   Breed/subspecies: BALB/c F1 Tg.AC transgenic.
DI   NCIt; C24017; Mouse fibrosarcoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 19-12-24; Version: 7
//
RX   PubMed=17952114; DOI=10.1038/sj.onc.1210866;
RA   Leder A., McMenamin J., Zhou F., Moran J.L., Beier D.R., Leder P.;
RT   "Genome-wide SNP analysis of Tg.AC transgenic mice reveals an
RT   oncogenic collaboration between v-Ha-ras and Ink4a, which is absent
RT   in p53 deficiency.";
RL   Oncogene 27:2456-2465(2008).
//