ID   CEBe033-A-8
AC   CVCL_C9YW
SY   SA001_KO_HGPRT_1; ISTEMe034-A-8
DR   BioSamples; SAMEA112964584
DR   hPSCreg; CEBe033-A-8
DR   Wikidata; Q123030893
RX   PubMed=37331109;
CC   From: Institut from Stem cell Therapy and Exploration of Monogenic diseases; Corbeil-Essonnes; France.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 5157; HPRT1.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
DI   NCIt; C61255; Lesch-Nyhan syndrome
DI   ORDO; Orphanet_510; Lesch-Nyhan syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B347 ! SA001
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 05-10-23; Last updated: 30-01-24; Version: 2
//
RX   PubMed=37331109; DOI=10.1016/j.scr.2023.103144;
RA   Boissart C., Chatrousse L., Poullion T., El-Kassar L.,
RA   Giraud-Triboult K., Benchoua A.;
RT   "CRISPR/Cas9-mediated generation of human embryonic stem cell
RT   sub-lines with HPRT1 gene knockout to model Lesch Nyhan disease.";
RL   Stem Cell Res. 71:103144-103144(2023).
//