ID   HEK293T/ACE2-TMPRSS2
AC   CVCL_C9BF
DR   GeneCopoeia; SL222
DR   Wikidata; Q123031594
CC   Group: SARS-CoV-2 research cell line.
CC   Characteristics: Expresses ACE2 and TMPRSS2 under the control of CMV promoters and mCherry under the control of a SV40 promoter (GeneCopoeia=SL222).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:13557; ACE2.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11876; TMPRSS2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0063 ! HEK293T
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 05-10-23; Last updated: 10-04-25; Version: 5
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