ID   HeLa-TetR-Cas9
AC   CVCL_C9AP
SY   cTT20
DR   Wikidata; Q123031631
RX   PubMed=26698661;
RX   PubMed=31626775;
CC   Population: African American.
CC   Characteristics: Expression of Cas9 can be induced by doxocycline (PubMed=26698661).
CC   Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 05-10-23; Last updated: 30-01-24; Version: 2
//
RX   PubMed=26698661; DOI=10.1016/j.molcel.2015.10.027;
RA   McKinley K.L., Sekulic N., Guo L.Y., Tsinman T., Black B.E.,
RA   Cheeseman I.M.;
RT   "The CENP-L-N complex forms a critical node in an integrated meshwork
RT   of interactions at the centromere-kinetochore interface.";
RL   Mol. Cell 60:886-898(2015).
//
RX   PubMed=31626775; DOI=10.1016/j.cell.2019.09.016;
RA   Feldman D., Singh A., Schmid-Burgk J.L., Carlson R.J., Mezger A.,
RA   Garrity A.J., Zhang F., Blainey P.C.;
RT   "Optical pooled screens in human cells.";
RL   Cell 179:787-799.e17(2019).
//