ID   SLC-44T
AC   CVCL_C8JF
DR   Wikidata; Q123033530
RX   PubMed=2148162;
RX   PubMed=8253353;
RX   PubMed=8518426;
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=SV40 LP-pUC13).
CC   Derived from site: In situ; Fetal small intestine; UBERON=UBERON_0002108.
CC   Cell type: Epithelial cell of intestine; CL=CL_0002563.
CC   Breed/subspecies: Wistar; RS=RS_0000955.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_C8JE ! SLC-44
SX   Female
AG   19FD
CA   Transformed cell line
DT   Created: 05-10-23; Last updated: 10-04-25; Version: 5
//
RX   PubMed=2148162; DOI=10.1159/000200370;
RA   Emami S., Chastre E., Nizard S., Di Gioia Y., Barbu V.D.,
RA   Taillemite J.-L., Ito S., Gespach C.;
RT   "Immortalization and neoplastic transformation of fetal rat intestinal
RT   epithelial cells: morphological and cytogenetic analysis,
RT   (proto)oncogene expression and effect of gamma-interferon on cell
RT   growth.";
RL   Digestion 46 Suppl. 2:74-91(1990).
//
RX   PubMed=8253353; DOI=10.1016/0016-5085(93)91076-t;
RA   Chastre E., Empereur S., Di Gioia Y., El Mahdani N.-E., Mareel M.M.,
RA   Vleminckx K.L., Van Roy F.M., Bex V., Emami S., Spandidos D.A.,
RA   Gespach C.;
RT   "Neoplastic progression of human and rat intestinal cell lines after
RT   transfer of the ras and polyoma middle T oncogenes.";
RL   Gastroenterology 105:1776-1789(1993).
//
RX   PubMed=8518426;
RA   Skrzydlo-Radomanska B., Pollard H., Slomka M., Emami S., Celinski K.,
RA   Chastre E., Gespach C.;
RT   "Enkephalinase activity in the intestinal epithelial cells of the
RT   fetus of 19 days and their immortalized and transformed counterparts
RT   the SLC-cell lines.";
RL   J. Physiol. Pharmacol. 44:65-71(1993).
//