ID   CHOL761h
AC   CVCL_C8H6
SY   CHO-L761h; CHOL76-1h
DR   Wikidata; Q123030925
RX   Patent=US6653101;
RX   PubMed=1707522;
CC   Characteristics: Expresses a mutant form of the Ad5 E1A gene product under the control of a SV40 promoter. Allows maximal transactivation of constructs that are under the control of a hCMV-MIE promoter (Patent=US6653101; PubMed=1707522).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein (Note=With p.Glu126Gly = R1176E1A).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 05-10-23; Last updated: 19-12-24; Version: 4
//
RX   Patent=US6653101;
RA   Cockett M.I., Bebbington C.R., Yarranton G.T.;
RT   "Recombinant DNA method and host cells.";
RL   Patent number US6653101, 25-Nov-2003.
//
RX   PubMed=1707522; DOI=10.1093/nar/19.2.319; PMCID=PMC333597;
RA   Cockett M.I., Bebbington C.R., Yarranton G.T.;
RT   "The use of engineered E1A genes to transactivate the hCMV-MIE
RT   promoter in permanent CHO cell lines.";
RL   Nucleic Acids Res. 19:319-325(1991).
//