ID   HHY41
AC   CVCL_C868
DR   Wikidata; Q54889517
RX   PubMed=7493648;
RX   PubMed=8607815;
RX   PubMed=9495533;
RX   PubMed=10580581;
CC   Doubling time: 39 hours (Note=At high density), 34 hours (Note=At low density) (PubMed=7493648).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   44Y
CA   Spontaneously immortalized cell line
DT   Created: 22-10-12; Last updated: 29-06-23; Version: 8
//
RX   PubMed=7493648; DOI=10.1006/excr.1995.1399;
RA   Kono Y., Yang S.-Y., Letarte M., Roberts E.A.;
RT   "Establishment of a human hepatocyte line derived from primary culture
RT   in a collagen gel sandwich culture system.";
RL   Exp. Cell Res. 221:478-485(1995).
//
RX   PubMed=8607815; DOI=10.1006/bbrc.1996.0454;
RA   Kono Y., Roberts E.A.;
RT   "Modulation of the expression of liver-specific functions in novel
RT   human hepatocyte lines cultured in a collagen gel sandwich
RT   configuration.";
RL   Biochem. Biophys. Res. Commun. 220:628-632(1996).
//
RX   PubMed=9495533; DOI=10.1016/S0168-1702(97)00115-9;
RA   zu Putlitz J., Roberts E.A., Wieland S.F., Kono Y., Blum H.E.;
RT   "Hepatitis B virus replication and viral antigen synthesis in
RT   hepatocyte lines derived from normal human liver.";
RL   Virus Res. 52:177-182(1997).
//
RX   PubMed=10580581; DOI=10.1016/S0168-8278(99)80285-2;
RA   McCloskey P., Edwards R.J., Tootle R., Selden C., Roberts E.A.,
RA   Hodgson H.J.F.;
RT   "Resistance of three immortalized human hepatocyte cell lines to
RT   acetaminophen and N-acetyl-p-benzoquinoneimine toxicity.";
RL   J. Hepatol. 31:841-851(1999).
//