ID   Vero PVR1/2 DKO hSLAM+
AC   CVCL_C7UT
SY   Vero deltaPVR1/2 hSLAM+ c1
DR   JCRB; JCRB1901
DR   Wikidata; Q123033771
RX   PubMed=36564197;
CC   Group: Non-human primate cell line.
CC   Virology: Not susceptible to infection by poliovirus. Useful for the isolation of measles virus (MeV) and rubella virus (RuV) as both viruses replicate efficiently in this cell line (PubMed=36564197).
CC   Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9S1N4; PVR1.
CC   Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9S1L1; PVR2.
CC   Transfected with: HGNC; 10903; SLAMF1.
CC   Transfected with: UniProtKB; P33967; B.cereus Bsr.
CC   Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
OX   NCBI_TaxID=60711; ! Chlorocebus sabaeus (Green monkey)
HI   CVCL_B3LS ! Vero PVR1/2 DKO
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 29-06-23; Last updated: 30-01-24; Version: 3
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RX   PubMed=36564197; DOI=10.1111/1348-0421.13047;
RA   Someya K., Okemoto-Nakamura Y., Kurata T., Kanbayashi D., Saito N.,
RA   Itamochi M., Otsuki N., Hanada K., Takeda M.;
RT   "Establishment of measles virus receptor-expressing Vero cells lacking
RT   functional poliovirus receptors.";
RL   Microbiol. Immunol. 67:166-170(2023).
//