ID   HMS50
AC   CVCL_C7T2
DR   Wikidata; Q117704494
RX   PubMed=7799951;
CC   Senescence: Capable of 40-50 PDL. One clone senesced at 68 PDL (PubMed=7799951).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met133Thr (c.398T>C); ClinVar=VCV000012357; Zygosity=Heterozygous (PubMed=7799951).
CC   Derived from site: In situ; Breast, interlobular stroma; UBERON=UBERON_8480033.
CC   Cell type: Fibroblast; CL=CL_0000057.
DI   NCIt; C3476; Li-Fraumeni syndrome
DI   ORDO; Orphanet_524; Li-Fraumeni syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C7T1 ! HME50
SX   Female
AG   31Y
CA   Finite cell line
DT   Created: 21-03-23; Last updated: 19-12-24; Version: 3
//
RX   PubMed=7799951; DOI=10.1128/mcb.15.1.425; PMCID=PMC231985;
RA   Shay J.W., Tomlinson G.E., Piatyszek M.A., Gollahon L.S.;
RT   "Spontaneous in vitro immortalization of breast epithelial cells from
RT   a patient with Li-Fraumeni syndrome.";
RL   Mol. Cell. Biol. 15:425-432(1995).
//