ID   DDT1-MF2 GR1
AC   CVCL_C7S1
SY   DDT1 MF2 GR1; GR1; DDT1 MF-2 GR
DR   Wikidata; Q117704284
RX   PubMed=4058427;
RX   PubMed=8314862;
CC   Characteristics: Glucocorticold receptor-poor variant. Growth of this cell line is completely resistant to the inhibitory action of glucocorticoids (PubMed=4058427; PubMed=8314862).
CC   Transformant: ChEBI; CHEBI_41922; Diethylstilbestrol.
CC   Derived from site: In situ; Vas deferens, smooth muscle; UBERON=UBERON_0004224.
DI   NCIt; C134567; Hamster ductus deferens leiomyosarcoma
OX   NCBI_TaxID=10036; ! Mesocricetus auratus (Golden hamster)
HI   CVCL_3459 ! DDT1-MF2
SX   Male
CA   Cancer cell line
DT   Created: 21-03-23; Last updated: 19-12-24; Version: 3
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RX   PubMed=4058427; DOI=10.1007/BF00219391;
RA   Norris J.S., Cornett L.E., Kohler P.O., MacLeod S.L., Syms A.J.,
RA   Smith R.G.;
RT   "Glucocorticoids induce a 29 000 Mr protein in DDT1 MF-2 smooth muscle
RT   cells but not in the DDT1 MF-2 GR glucocorticoid resistant variant.";
RL   Mol. Cell. Biochem. 68:79-85(1985).
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RX   PubMed=8314862; DOI=10.1002/jcp.1041560113;
RA   Fan W.-M., Cooper T.M., Norris J.S.;
RT   "Characterization of selective glucocorticoid-dependent responses in a
RT   glucocorticoid-resistant smooth muscle tumor cell line.";
RL   J. Cell. Physiol. 156:88-95(1993).
//