ID   MCF10A-EGFR1m-1
AC   CVCL_C7Q2
SY   MCF10A-EGFR-1_type-01; 06M01002
DR   CancerTools; 161168
DR   Wikidata; Q117704643
RX   PubMed=27840973;
WW   Info; FTRP; -; https://www.fmu.ac.jp/home/trc/en/contract-research-provision/human-gene-overexpressing-cell-lines/
CC   Part of: Fukushima Translational Research Project gene-overexpressing cell lines panel.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Leu858Arg (c.2573T>G)).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0598 ! MCF-10A
SX   Female
AG   36Y
CA   Spontaneously immortalized cell line
DT   Created: 21-03-23; Last updated: 10-04-25; Version: 5
//
RX   PubMed=27840973; DOI=10.3892/or.2016.5227; PMCID=PMC5355725;
RA   Hoshi H., Hiyama G., Ishikawa K., Inageda K., Fujimoto J.,
RA   Wakamatsu A., Togashi T., Kawamura Y., Takahashi N., Higa A.,
RA   Goshima N., Semba K., Watanabe S., Takagi M.;
RT   "Construction of a novel cell-based assay for the evaluation of
RT   anti-EGFR drug efficacy against EGFR mutation.";
RL   Oncol. Rep. 37:66-76(2017).
//