ID   HAP1 MDK (-)
AC   CVCL_C6Y2
SY   HZGHC007906c008; MDK knockout cell line 2bp insertion in exon 4
DR   Horizon_Discovery; HZGHC007906c008
DR   Wikidata; Q117704470
RX   DOI=10.12688/f1000research.130587.1;
CC   Group: Haploid karyotype cell line.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 6972; MDK.
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y019 ! HAP1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 21-03-23; Last updated: 29-06-23; Version: 2
//
RX   DOI=10.12688/f1000research.130587.1;
RA   Ayoubi R., Southern K., Laflamme C.;
RT   "The identification of high-performing antibodies for midkine for use
RT   in western blot and immunoprecipitation.";
RL   F1000Research 12:148.1-148.8(2023).
//