ID   OVTW59-P4
AC   CVCL_C6VT
SY   OVTW59 P4; OVTW-59-P4; OVTW-59-4
DR   Wikidata; Q117704765
RX   PubMed=17952116;
RX   PubMed=34824343;
CC   Population: Chinese; Taiwan.
CC   Characteristics: High invasive phenotype. Selected from parent cell line for invasion phenotype using Matrigel-coated transwell membranes. P4 are P3-derived cells that had invaded through the Matrigel (PubMed=17952116).
CC   Doubling time: 19 hours (PubMed=17952116).
CC   Karyotypic information: XXX,t(3;12),t(5;8),t(6;15),t(11;12),t(15;22),del(7)(q22),-4,+12,+14,+14,-18,-19,+21,-22,-22 (PubMed=17952116).
CC   Derived from site: In situ; Ovary, epithelium; UBERON=UBERON_0004911.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
DI   NCIt; C7979; Ovarian endometrioid adenocarcinoma
DI   ORDO; Orphanet_454723; Endometrioid carcinoma of ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C6VS ! OVTW59-P3
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 21-03-23; Last updated: 29-06-23; Version: 2
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RX   PubMed=17952116; DOI=10.1038/sj.onc.1210864;
RA   Torng P.-L., Lee Y.-C.G., Huang C.-Y.F., Ye J.-H., Lin Y.-S.,
RA   Chu Y.-W., Huang S.-C., Cohen P., Wu C.-W., Lin C.-T.;
RT   "Insulin-like growth factor binding protein-3 (IGFBP-3) acts as an
RT   invasion-metastasis suppressor in ovarian endometrioid carcinoma.";
RL   Oncogene 27:2137-2147(2008).
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RX   PubMed=34824343; DOI=10.1038/s41598-021-02400-1; PMCID=PMC8616920;
RA   Shih H.-J., Chang H.-F., Chen C.-L., Torng P.-L.;
RT   "Differential expression of hypoxia-inducible factors related to the
RT   invasiveness of epithelial ovarian cancer.";
RL   Sci. Rep. 11:22925.1-22925.13(2021).
//