ID   FM92
AC   CVCL_C615
SY   FM-92
DR   cancercelllines; CVCL_C615
DR   Cosmic; 851402
DR   Cosmic; 1006227
DR   Cosmic; 1047683
DR   Cosmic; 2163782
DR   ECACC; 13012429
DR   ESTDAB; ESTDAB-032
DR   GEO; GSM156044
DR   IARC_TP53; 26109
DR   Progenetix; CVCL_C615
DR   Wikidata; Q54835074
RX   PubMed=9288767;
RX   PubMed=17260012;
RX   PubMed=23851445;
CC   Sequence variation: Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (PubMed=17260012).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17260012; PubMed=23851445).
CC   Omics: Variations; Array-based CGH.
ST   Source(s): ECACC=13012429; ESTDAB=ESTDAB-032
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D13S317: 11,12
ST   D16S539: 13,14
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   FGA: 20
ST   TH01: 8
ST   TPOX: 8
ST   vWA: 15,19
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 10-04-25; Version: 20
//
RX   PubMed=9288767;
RA   Guldberg P., thor Straten P., Birck A., Ahrenkiel V., Kirkin A.F.,
RA   Zeuthen J.;
RT   "Disruption of the MMAC1/PTEN gene by deletion or mutation is a
RT   frequent event in malignant melanoma.";
RL   Cancer Res. 57:3660-3663(1997).
//
RX   PubMed=17260012; DOI=10.1038/sj.onc.1210252;
RA   Jonsson G., Dahl C., Staaf J., Sandberg T., Bendahl P.-O., Ringner M.,
RA   Guldberg P., Borg A.;
RT   "Genomic profiling of malignant melanoma using tiling-resolution
RT   arrayCGH.";
RL   Oncogene 26:4738-4748(2007).
//
RX   PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006;
RA   Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L.,
RA   Borg A., Pawelec G., Guldberg P.;
RT   "Mutual exclusivity analysis of genetic and epigenetic drivers in
RT   melanoma identifies a link between p14 ARF and RARbeta signaling.";
RL   Mol. Cancer Res. 11:1166-1178(2013).
//