ID   CC531mdr+
AC   CVCL_C5RJ
DR   ChEMBL-Cells; CHEMBL3833761
DR   Wikidata; Q116048692
RX   PubMed=7903965;
RX   PubMed=14727116;
CC   Characteristics: Multidrug resistant, in addition to colchicine it also is resistant against actinomycin D, daunorubicin, doxorubicin and vinblastine (PubMed=7903965).
CC   Selected for resistance to: ChEBI; CHEBI_23359; Colchicine.
CC   Transformant: ChEBI; CHEBI_73755; 1,2-dimethylhydrazine (DMH).
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
CC   Breed/subspecies: WAG/Rij; RS=RS_0000969.
DI   NCIt; C63866; Adenocarcinoma of the rat colon
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_0206 ! CC531
SX   Male
AG   Adult
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 10-04-25; Version: 6
//
RX   PubMed=7903965; DOI=10.1111/j.1349-7006.1993.tb02822.x; PMCID=PMC5919088;
RA   Gheuens E., van der Heyden S., Elst H., Eggermont A.M.M.,
RA   Van Oosterom A.T., De Bruijn E.;
RT   "Multidrug resistance in rat colon carcinoma cell lines CC531,
RT   CC531mdr+ and CC531rev.";
RL   Jpn. J. Cancer Res. 84:1201-1208(1993).
//
RX   PubMed=14727116; DOI=10.1007/s00424-003-1216-7;
RA   Golstein P.E., Daifi A., Crutzen R., Boom A., Van Driessche W.,
RA   Beauwens R.;
RT   "Hypotonic cell swelling stimulates permeability to cAMP in a rat
RT   colonic cell line.";
RL   Pflugers Arch. 447:845-854(2004).
//