ID   FM48
AC   CVCL_C587
DR   cancercelllines; CVCL_C587
DR   Cosmic; 1047665
DR   GEO; GSM156027
DR   IARC_TP53; 26092
DR   Progenetix; CVCL_C587
DR   Wikidata; Q54835042
RX   PubMed=8665567;
RX   PubMed=8968104;
RX   PubMed=9288767;
RX   PubMed=17260012;
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=17260012).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17260012).
CC   Omics: Array-based CGH.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 05-10-23; Version: 16
//
RX   PubMed=8665567; DOI=10.1007/s002620050272;
RA   Kirkin A.F., thor Straten P., Zeuthen J.;
RT   "Differential modulation by interferon gamma of the sensitivity of
RT   human melanoma cells to cytolytic T cell clones that recognize
RT   differentiation or progression antigens.";
RL   Cancer Immunol. Immunother. 42:203-212(1996).
//
RX   PubMed=8968104;
RA   Bartkova J., Lukas J., Guldberg P., Alsner J., Kirkin A.F.,
RA   Zeuthen J., Bartek J.;
RT   "The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently
RT   altered in melanoma pathogenesis.";
RL   Cancer Res. 56:5475-5483(1996).
//
RX   PubMed=9288767;
RA   Guldberg P., thor Straten P., Birck A., Ahrenkiel V., Kirkin A.F.,
RA   Zeuthen J.;
RT   "Disruption of the MMAC1/PTEN gene by deletion or mutation is a
RT   frequent event in malignant melanoma.";
RL   Cancer Res. 57:3660-3663(1997).
//
RX   PubMed=17260012; DOI=10.1038/sj.onc.1210252;
RA   Jonsson G., Dahl C., Staaf J., Sandberg T., Bendahl P.-O., Ringner M.,
RA   Guldberg P., Borg A.;
RT   "Genomic profiling of malignant melanoma using tiling-resolution
RT   arrayCGH.";
RL   Oncogene 26:4738-4748(2007).
//