ID   Mel-WL
AC   CVCL_C504
DR   cancercelllines; CVCL_C504
DR   Cosmic; 2163814
DR   ESTDAB; ESTDAB-095
DR   Wikidata; Q54905145
RX   PubMed=15592718;
RX   PubMed=23851445;
CC   HLA typing: A*11:01,01:01; B*35:01,51:01:01; C*04:01:01,12:03; DPB1*04:02,10:01; DQB1*03:01:01,05:01; DRB1*01:01,11:01 (PubMed=15592718).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23851445).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Pro81Ser (c.241C>T) (p.Thr95Ile, c.284C>T); ClinVar=VCV000664812; Zygosity=Unspecified (PubMed=23851445).
CC   Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45del (c.133_135delTCT); ClinVar=VCV000017576; Zygosity=Unspecified (PubMed=23851445).
ST   Source(s): ESTDAB=ESTDAB-095
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 12,13
ST   D3S1358: 14,15
ST   D5S818: 10,13
ST   D7S820: 9
ST   FGA: 21,24
ST   TH01: 9,9.3
ST   TPOX: 8
ST   vWA: 15,17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 15
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RX   PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966;
RA   Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A.,
RA   Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G.,
RA   Garrido F.;
RT   "High frequency of homozygosity of the HLA region in melanoma cell
RT   lines reveals a pattern compatible with extensive loss of
RT   heterozygosity.";
RL   Cancer Immunol. Immunother. 54:141-148(2005).
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RX   PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006;
RA   Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L.,
RA   Borg A., Pawelec G., Guldberg P.;
RT   "Mutual exclusivity analysis of genetic and epigenetic drivers in
RT   melanoma identifies a link between p14 ARF and RARbeta signaling.";
RL   Mol. Cancer Res. 11:1166-1178(2013).
//