ID   AC-10
AC   CVCL_C4MC
DR   Wikidata; Q116048470
RX   PubMed=9426306;
CC   Doubling time: ~24 hours (Note=In the presence of 20 ng/ml FGF2), ~48 hours (Note=Without FGF2) (PubMed=9426306).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen (Note=With p.Leu156_Thr708del = Truncated).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryonic brain, mesencephalon; UBERON=UBERON_0009616.
CC   Breed/subspecies: Sprague Dawley; RS=RS_0000681.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Sex unspecified
AG   14FD
CA   Transformed cell line
DT   Created: 15-12-22; Last updated: 14-08-25; Version: 6
//
RX   PubMed=9426306; DOI=10.1007/s004410050989;
RA   Truckenmiller, Mary Ellen
RA   Tornatore, Carlo
RA   Wright, Renee Darnell
RA   Dillon-Carter, Ora
RA   Meiners, Sally
RA   Geller, Herbert M.
RA   Freed, William J.
RT   "A truncated SV40 large T antigen lacking the p53 binding domain
RT   overcomes p53-induced growth arrest and immortalizes primary
RT   mesencephalic cells.";
RL   Cell Tissue Res. 291:175-189(1998).
//