ID   T47D/XBP1
AC   CVCL_C4MA
DR   Wikidata; Q116050610
RX   PubMed=17660348;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 12801; XBP1.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0553 ! T-47D
SX   Female
AG   54Y
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 05-10-23; Version: 4
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RX   PubMed=17660348; DOI=10.1096/fj.06-7990com;
RA   Gomez B.P., Riggins R.B., Shajahan A.N., Klimach U., Wang A.-F.,
RA   Crawford A.C., Zhu Y.-L., Zwart A., Wang M.-Y., Clarke R.;
RT   "Human X-box binding protein-1 confers both estrogen independence and
RT   antiestrogen resistance in breast cancer cell lines.";
RL   FASEB J. 21:4013-4027(2007).
//